Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates

نویسندگان

  • Katarzyna Gobis
  • Henryk Foks
  • Zofia Zwolska
  • Ewa Augustynowicz-Kopeć
  • Marek L. Główka
  • Andrzej Olczak
  • Michał Sabisz
چکیده

ABSTRACT New dimethyl benzoylcarbonohydrazonodithioates were obtained by CS2 addition to arylcarboxylic acid hydrazides and methylation of the formed adduct. The new derivatives were tested for their activity against Mycobacterium tuberculosis. Some compounds exhibited high activity toward sensitive and resistant strains. GRAPHICAL ABSTRACT

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عنوان ژورنال:

دوره 142  شماره 

صفحات  -

تاریخ انتشار 2011